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Abstract：
BACKGROUND: Needleless transcutaneous pneumatic injections (TPIs) are a minimally invasive way to deliver the solution into the skin for therapeutic purposes. The suggested action mechanisms of TPI therapy include mechanical stimulation, immediate tissue shrinkage and late wound healing.
METHODS: Thirteen Korean patients were treated with TPI for atrophic skin disorders, including acne scars, striae albae, post-furuncle, or carbuncle scars, and horizontal wrinkles with lipoatrophy. At each TPI treatment session, a single pass was made along with the atrophic skin lesions without overlapping. Thereafter, two dermatologists objectively evaluated the clinical improvement in the lesions in the photographs via the global aesthetic improvement scale (GAIS).
RESULTS: One month after the final treatment, the overall mean GAIS score was 2.3 ± 0.8. Six of the 13 (46.2%) patients exhibited clinical improvement of grade 3, five (38.5%) patients grade 2 and two (15.4%) patients grade 1. The overall mean subjective satisfaction score with the TPI treatment was 2.3 ± 0.9. Six of the 13 (46.2%) patients achieved subjective satisfaction of grade 3, six (46.2%) patients grade 2 and one (7.7%) patient grade 0.
CONCLUSIONS: The present study demonstrated that the TPI treatment is effective and safe for treating atrophic skin disorders of varying causes in Korean patients.
METHODS: Thirteen Korean patients were treated with TPI for atrophic skin disorders, including acne scars, striae albae, post-furuncle, or carbuncle scars, and horizontal wrinkles with lipoatrophy. At each TPI treatment session, a single pass was made along with the atrophic skin lesions without overlapping. Thereafter, two dermatologists objectively evaluated the clinical improvement in the lesions in the photographs via the global aesthetic improvement scale (GAIS).
RESULTS: One month after the final treatment, the overall mean GAIS score was 2.3 ± 0.8. Six of the 13 (46.2%) patients exhibited clinical improvement of grade 3, five (38.5%) patients grade 2 and two (15.4%) patients grade 1. The overall mean subjective satisfaction score with the TPI treatment was 2.3 ± 0.9. Six of the 13 (46.2%) patients achieved subjective satisfaction of grade 3, six (46.2%) patients grade 2 and one (7.7%) patient grade 0.
CONCLUSIONS: The present study demonstrated that the TPI treatment is effective and safe for treating atrophic skin disorders of varying causes in Korean patients.
摘要：
背景:无针经皮气动注射(TPI)是为了治疗目的将溶液递送到皮肤中的微创方式。TPI治疗的建议作用机制包括机械刺激，立即组织收缩和晚期伤口愈合。
方法：13名韩国患者接受TPI治疗萎缩性皮肤病，包括痤疮疤痕,纹状体，post-furbut,或carbuble疤痕，和脂肪萎缩的水平皱纹。在每个TPI治疗阶段，一次通过与萎缩性皮肤病变一起进行，没有重叠。此后,两名皮肤科医生通过全球美学改善量表(GAIS)客观评估了照片中病变的临床改善情况.
结果：最终治疗后一个月，总体平均GAIS评分为2.3±0.8.13名患者中有6名（46.2％）表现出3级临床改善，5名（38.5％）患者为2级，2名（15.4％）患者为1级。TPI治疗的总体平均主观满意度评分为2.3±0.9。13名患者中有6名（46.2％）获得了3级的主观满意度，6名（46.2％）获得了2级的主观满意度，1名（7.7％）获得了0级的主观满意度。
结论：本研究表明，TPI治疗对治疗韩国患者不同原因的萎缩性皮肤病是有效和安全的。
方法：13名韩国患者接受TPI治疗萎缩性皮肤病，包括痤疮疤痕,纹状体，post-furbut,或carbuble疤痕，和脂肪萎缩的水平皱纹。在每个TPI治疗阶段，一次通过与萎缩性皮肤病变一起进行，没有重叠。此后,两名皮肤科医生通过全球美学改善量表(GAIS)客观评估了照片中病变的临床改善情况.
结果：最终治疗后一个月，总体平均GAIS评分为2.3±0.8.13名患者中有6名（46.2％）表现出3级临床改善，5名（38.5％）患者为2级，2名（15.4％）患者为1级。TPI治疗的总体平均主观满意度评分为2.3±0.9。13名患者中有6名（46.2％）获得了3级的主观满意度，6名（46.2％）获得了2级的主观满意度，1名（7.7％）获得了0级的主观满意度。
结论：本研究表明，TPI治疗对治疗韩国患者不同原因的萎缩性皮肤病是有效和安全的。
