关键词: DeNovo Osteochondral allograft Osteochondral autologous transplant Osteochondral lesion of talus PRP

Mesh : Biological Therapy / methods Cartilage, Articular / pathology surgery Humans Osteochondroma / pathology physiopathology surgery Talus / pathology physiopathology Tissue Transplantation / methods Treatment Outcome

来  源:   DOI:10.1016/j.ocl.2017.03.008

Abstract:
Symptomatic osteochondral lesions of the talus remain a challenging problem due to inability for cartilage lesions to heal. Numerous treatment options exist, including nonoperative management, marrow stimulating techniques, and autograft-allograft. Arthroscopic marrow stimulation forms fibrocartilage that has been shown to be biomechanically weaker than hyaline cartilage. Restorative tissue transplantation options are being used more for larger and cystic lesions. Newer biologics and particulated juvenile cartilage are currently under investigation for possible clinical efficacy. This article provides an evidenced-based summary of available literature on the use of biologics for treatment of osteochondral lesions of the talus.
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