METHODS: Recent epidemiology and animal studies have provided further insight into the pathophysiology, clinical findings, social and economic impacts of noise-induced hearing loss. Furthermore, it is recently shown that acoustic trauma is associated with vestibular dysfunction, with associated dizziness that is not always measurable with current techniques. Deliberation of the prevalence, treatment and prevention of noise-induced hearing loss is important and timely. Currently, prevention and protection are the first lines of defence, although promising protective effects are emerging from multiple different pharmaceutical agents, such as steroids, antioxidants and neurotrophins.
CONCLUSIONS: This review provides a comprehensive update on the pathophysiology, investigations, prevalence of asymmetry, associated symptoms, and current strategies on the prevention and treatment of noise-induced hearing loss.
方法:最近的流行病学和动物研究为病理生理学提供了进一步的见解,临床发现,噪声引起的听力损失的社会和经济影响。此外,最近表明,声学创伤与前庭功能障碍有关,与相关的头晕,这并不总是可以用当前的技术来衡量。对患病率的审议,治疗和预防噪声引起的听力损失是重要和及时的。目前,预防和保护是第一道防线,虽然有希望的保护作用正在出现从多种不同的药物,比如类固醇,抗氧化剂和神经营养因子。
结论:这篇综述提供了关于病理生理学的全面更新,调查,不对称的普遍性,相关症状,以及预防和治疗噪声引起的听力损失的当前策略。