Abstract：
Several evidence-informed treatment guidelines recommend against the use of typical antipsychotics in patients with Parkinson\'s disease; of the atypical antipsychotics, clozapine and quetiapine are preferred. The purpose of this study is to determine the frequency with which potentially inappropriate antipsychotics are dispensed to older adults in Nova Scotia who are on levodopa-containing medications. In this cohort, 59.9% were dispensed a preferred atypical antipsychotic and 12.6% a potentially harmful typical antipsychotic. Our results suggest that potentially inappropriate prescribing practices are common in the neuropsychiatric management of patients with parkinsonism and that there is an opportunity for education and improvement in prescribing practices.
摘要：
一些有证据的治疗指南建议在帕金森病患者中不使用典型的抗精神病药物；在非典型抗精神病药物中，优选氯氮平和喹硫平。这项研究的目的是确定在新斯科舍省服用含左旋多巴药物的老年人分配潜在不适当的抗精神病药物的频率。在这个队列中，59.9％的人被分配了首选的非典型抗精神病药，12.6％的人被分配了潜在有害的典型抗精神病药。我们的结果表明，在帕金森病患者的神经精神管理中，潜在的不适当的处方做法很常见，并且有机会进行教育和改进处方做法。
