METHODS: A retrospective study of microbiologically proven Acinetobacter spp. endophthalmitis was carried out from 2010 to 2015. The data collected included age, type of endophthalmitis, best-corrected visual acuity (BCVA), species involved, and antibiotic susceptibility pattern. The primary outcomes measured were anatomical outcomes in terms of globe integrity and functional outcome as BCVA at last follow-up.
RESULTS: Eleven patients out of 3004 patients who underwent surgery for endophthalmitis were due to Acinetobacter spp. Seven cases (63.6%) were both smear and culture positive; there were two cases (18%) each of A. haemolyticus and A. baumanii. Four cases (36%) were only culture positive with negative smear. Three cases (27.2%) were polymicrobial. Ten cases (91%) were susceptible to amikacin and nine (82%) to ciprofloxacin. Six (54.5%) were resistant to ceftazidime. Mean logMAR BCVA improved to 1.8 (20/1330) from an initial 2.5 (20/6839). Pthisis bulbi was seen in two cases (18%).
CONCLUSIONS: Even though the outcomes of Acinetobacter spp. endophthalmitis are modest to poor, outcomes following intervention are relatively good for A. haemolyticus. These cases have good susceptibility to amikacin, but are often resistant to ceftazidime.
方法:对微生物证实的不动杆菌属的回顾性研究。2010年至2015年进行了眼内炎。收集的数据包括年龄,眼内炎的类型,最佳矫正视力(BCVA),涉及的物种,和抗生素敏感性模式。测量的主要结果是在最后一次随访时作为BCVA的全球完整性和功能结果方面的解剖学结果。
结果:3004例接受眼内炎手术的患者中有11例患者是由于不动杆菌属。涂片和培养均为阳性的7例(63.6%);溶血性弧菌和鲍曼不动杆菌各2例(18%)。4例(36%)仅培养阳性,涂片阴性。3例(27.2%)为多微生物。10例(91%)对阿米卡星敏感,9例(82%)对环丙沙星敏感。6例(54.5%)对头孢他啶耐药。平均logMARBCVA从最初的2.5(20/6839)提高到1.8(20/1330)。在2例(18%)中发现了Pthisisbulbi。
结论:即使不动杆菌属的结果。眼内炎是适度到贫穷的,溶血杆菌干预后的结局相对较好.这些病例对阿米卡星具有良好的敏感性,但通常对头孢他啶有抵抗力。