Abstract：
Networked 21st century society, globalization, and communications technologies are paralleled by the rise of electromagnetic energy intensity in our environments and the growing pressure of the environtome on human biology and health. The latter is the entire complement of environmental factors, including the electromagnetic energy and the technologies that generate them, enacting on the digital citizen in the new century. Electromagnetic pulse (EMP) irradiation might have serious damaging effects not only on electronic equipment but also in the whole organism and reproductive health, through nonthermal effects and oxidative stress. We sought to determine whether EMP exposure (1) induces biological damage on reproductive health and (2) the extent to which selenium-rich Cordyceps fungi (daily coadministration) offer protection on the testicles and spermatozoa. In a preclinical randomized study, 3-week-old male BALB/c mice were repeatedly exposed to EMP (peak intensity 200 kV/m, pulse edge 3.5 ns, pulse width 15 ns, 0.1 Hz, and 400 pulses/day) 5 days per week for four consecutive weeks, with or without coadministration of daily selenium-rich Cordyceps fungi (100 mg/kg). Testicular index and spermatozoa formation were measured at baseline and 1, 7, 14, 28, and 60 day time points after EMP exposure. The group without Cordyceps cotreatment displayed decreased spermatozoa formation, shrunk seminiferous tubule diameters, and diminished antioxidative capacity at 28 and 60 days after exposure (p < 0.05). The Cordyceps daily cotreatment alleviated the testicular damage by EMP exposure, increased spermatozoa formation, and reduced apoptotic spermatogenic cells. These observations warrant further preclinical and clinical studies as an innovative approach for potential protection against electromagnetic radiation in the current age of networked society and digital citizenship.
摘要：
网络化的21世纪社会，全球化,和通信技术与我们环境中电磁能量强度的上升以及环境对人类生物学和健康的日益增长的压力并行。后者是环境因素的完整补充，包括电磁能和产生它们的技术，在新世纪制定数字公民。电磁脉冲（EMP）辐射可能不仅对电子设备，而且对整个生物体和生殖健康产生严重的破坏性影响，通过非热效应和氧化应激。我们试图确定EMP暴露（1）是否会对生殖健康造成生物损害，以及（2）富硒虫草真菌（每日共同给药）对睾丸和精子的保护程度。在一项临床前随机研究中,3周龄雄性BALB/c小鼠反复暴露于EMP（峰值强度200kV/m，脉冲边沿3.5ns，脉冲宽度15ns，0.1Hz,和400脉冲/天）连续四周每周5天，每天有或没有共同施用富硒虫草真菌（100mg/kg）。在基线和EMP暴露后1、7、14、28和60天时间点测量睾丸指数和精子形成。无冬虫夏草共治疗组精子形成减少，缩小的精细管直径，暴露后28天和60天的抗氧化能力下降（p<0.05）。冬虫夏草每日共同治疗减轻了电磁脉冲暴露对睾丸的损害，精子形成增加，减少生精细胞的凋亡。这些观察结果值得进一步的临床前和临床研究，作为在当前网络化社会和数字公民时代防止电磁辐射的创新方法。
