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Abstract：
Purpose: The aim of this study is to investigate self- and parent-rated quality of life (QoL) in children with a reading disability (RD) and the impact of comorbid psychopathology, with special focus on age and gender differences. Methods: Using the Dyslexia Differential Diagnosis Maastricht-Hungarian standard test, 127 children (aged < 18) were included in the RD group and 81 in the control group. To measure comorbid psychopathology, the Strengths and Difficulties Questionnaire (SDQ) was administered. To evaluate the children\'s QoL self- and parent-rated versions of the Measure of Quality of Life for Children and Adolescents (ILK) were used. Group differences in QoL and psychopathology were assessed using Mann-Whitney U-tests. Moderated mediational models were tested in which comorbid psychopathology mediated the relationship between group membership and self- and parent-rated QoL, which was dependent on gender. Child\'s age and parents\' level of education were included as covariates. Results: The RD group showed lower QoL than the controls in several domains, according to the parent-report, while no differences between the two groups were found, according to self-report. In boys, results revealed conditional and indirect effects of group membership on self- and parent-rated QoL through comorbid psychopathology (-0.046, BCa 95% CI: -0.135 to 0.043 and 0.064, BCa 95% CI: 0.024-0.111, respectively) as well as a conditional direct effect of group membership on parent-reported (-0.098, BCa 95% CI: 0.012-0.184), but not self-rated, QoL. No relationship was found for girls. Conclusions: This study highlights the importance of measuring QoL and comorbid psychopathology in children with RDs from more sources and accounting for gender and age differences.
摘要：
目的：这项研究的目的是调查阅读障碍（RD）儿童的自我和父母评估的生活质量（QoL）以及合并症精神病理学的影响，特别关注年龄和性别差异。方法：使用阅读障碍鉴别诊断马斯特里赫特-匈牙利标准测试，RD组包括127名儿童（<18岁），对照组包括81名儿童。为了测量精神病理学合并症，实施优势和困难问卷(SDQ)。为了评估儿童的QoL，使用了儿童和青少年生活质量测量（ILK）的自我和父母评估版本。使用Mann-WhitneyU检验评估QoL和精神病理学的群体差异。对调节的中介模型进行了测试，其中合并症的精神病理学介导了组成员资格与自我和父母评估的QoL之间的关系，这取决于性别。儿童的年龄和父母的教育水平作为协变量。结果：RD组在几个领域的QoL低于对照组，根据家长报告，虽然两组之间没有发现差异，根据自我报告。在男孩中，结果显示，通过合并症精神病理学（-0.046，BCa95％CI：-0.135至0.043和0.064，BCa95％CI：0.024-0.111，BCa95％CI：0.024-0.111），以及组成员对父母报告的条件直接影响（-0.098，BCa95％CI：0.012-0.184），但不是自我评价的，QoL.没有发现女孩的关系。结论：这项研究强调了从更多来源测量RD儿童的QoL和合并症精神病理学的重要性，并考虑了性别和年龄差异。
