Mesh : Anastomosis, Surgical / adverse effects methods Anastomotic Leak / classification therapy Chylous Ascites / classification etiology therapy Consensus Female Humans Internationality Male Pancreatectomy / adverse effects methods Pancreatic Neoplasms / surgery Postoperative Complications / classification therapy Prognosis Risk Assessment Severity of Illness Index Treatment Outcome

来  源:   DOI:10.1016/j.surg.2016.06.058   PDF(Sci-hub)

Abstract:
Recent literature suggests that chyle leak may complicate up to 10% of pancreatic resections. Treatment depends on its severity, which may include chylous ascites. No international consensus definition or grading system of chyle leak currently is available.
The International Study Group on Pancreatic Surgery, an international panel of pancreatic surgeons working in well-known, high-volume centers, reviewed the literature and worked together to establish a consensus on the definition and classification of chyle leak after pancreatic operation.
Chyle leak was defined as output of milky-colored fluid from a drain, drain site, or wound on or after postoperative day 3, with a triglyceride content ≥110 mg/dL (≥1.2 mmol/L). Three different grades of severity were defined according to the management needed: grade A, no specific intervention other than oral dietary restrictions; grade B, prolongation of hospital stay, nasoenteral nutrition with dietary restriction, total parenteral nutrition, octreotide, maintenance of surgical drains, or placement of new percutaneous drains; and grade C, need for other more invasive in-hospital treatment, intensive care unit admission, or mortality.
This classification and grading system for chyle leak after pancreatic resection allows for comparison of outcomes between series. As with the other the International Study Group on Pancreatic Surgery consensus statements, this classification should facilitate communication and evaluation of different approaches to the prevention and treatment of this complication.
摘要:
最近的文献表明,乳糜渗漏可能会使多达10%的胰腺切除术复杂化。治疗取决于其严重程度,其中可能包括乳糜腹水。目前尚无国际共识的乳糜渗漏定义或分级系统。
国际胰腺手术研究小组,一个由胰腺外科医生组成的国际小组,高容量中心,回顾了文献,并共同努力就胰腺手术后乳糜漏的定义和分类达成共识。
Chyle泄漏被定义为从排水口输出的乳白色液体,排水现场,或术后第3天或之后的伤口,甘油三酯含量≥110mg/dL(≥1.2mmol/L)。根据所需的管理定义了三个不同的严重程度等级:A级,除口服饮食限制外,无特定干预措施;B级,延长住院时间,限制饮食的鼻肠营养,全胃肠外营养,奥曲肽,维护外科引流管,或放置新的经皮引流管;以及C级,需要其他更具侵入性的院内治疗,重症监护室入院,或死亡率。
这种胰腺切除术后乳糜漏的分类和分级系统可以比较系列之间的结果。与其他国际胰腺手术研究小组的共识声明一样,这种分类应有助于沟通和评估预防和治疗这种并发症的不同方法.
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