PDF(Sci-hub)
Abstract：
Vascular prosthetic graft infection (VPGI) is associated with high mortality and morbidity. An early and accurate diagnosis is essential in order to give the most appropriate treatment. The case is presented of a 74 year old male subjected to an aortobifemoral bypass graft, with clinical suspicion of VPGI with inconclusive tests. Later on an 18F-FDG PET/CT study showed a pathological uptake, suggestive of periprosthetic infection, as well as an incidental pulmonary lesion, suggestive of a primary neoplasm. A new 18F-FDG PET/CT showed a significant improvement in the uptake by the vascular graft after prolonged antibiotic treatment. 18F-FDG is a promising tracer for detecting VPGI as the accumulated activated white cells at the infection site have a high demand for 18F-FDG, and could help define the response to antibiotic treatment.
摘要：
血管人工移植物感染（VPGI）与高死亡率和高发病率相关。早期和准确的诊断是必要的，以给予最适当的治疗。该病例是一名74岁的男性接受了主动脉口经旁路移植术，临床怀疑VPGI，测试不确定。后来在18F-FDGPET/CT研究显示病理摄取，提示假体周围感染，以及附带的肺部病变，提示原发性肿瘤。新的18F-FDGPET/CT显示，经过长时间的抗生素治疗后，血管移植物的摄取显着改善。18F-FDG是检测VPGI的有前途的示踪剂，因为感染部位积累的活化白细胞对18F-FDG有很高的需求，并可以帮助确定对抗生素治疗的反应。
