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Abstract：
Genistein is a phytoestrogen with diverse biological activities. It is a potent antioxidant and antibrowning agent in in vivo and in vitro. Genistein acts as a preventative and therapeutic effects for cancers, postmenopausal syndrome, osteoporosis and cardiovascular diseases in animals and humans. Gensitein possesses cancer related enzyme-inhibitory effect and substantially inhibits skin carcinogenesis and cutaneous aging induced by ultraviolet (UV) light in mice and photodamage in humans. Two-stage skin carcinogenesis showed genistein exhibited a moderate inhibition of ornithine decarboxylase activity through blockage of DNA adducts formation. The anticancer, anti-inflammatory, cardio-protective and enzyme-inhibitory effects of genistein might be related to their antioxidant activities. Genistein also altered the Maillard reaction pathway by trapping the advanced glycation end products (AGEs) both in biological and protein-lactose suspensions. As a result, soy isoflavone can be used to enrich or fortify different types of food products.
摘要：
金雀异黄素是一种具有多种生物活性的植物雌激素。它是体内和体外有效的抗氧化剂和抗褐变剂。金雀异黄素作为癌症的预防和治疗作用，绝经后综合征,骨质疏松症和心血管疾病在动物和人类。Gensitin具有癌症相关的酶抑制作用，并基本上抑制了小鼠中紫外线（UV）光引起的皮肤癌变和皮肤老化以及人类的光损伤。两阶段皮肤癌变表明，金雀异黄素通过阻断DNA加合物的形成对鸟氨酸脱羧酶活性有适度的抑制作用。抗癌，抗炎,金雀异黄素的心脏保护和酶抑制作用可能与其抗氧化活性有关。金雀异黄素还通过捕获生物和蛋白质-乳糖悬浮液中的晚期糖基化终产物（AGEs）来改变美拉德反应途径。因此,大豆异黄酮可用于丰富或强化不同类型的食品。
