关键词: Flow-limiting segment Lateral pressure Stent Tracheobronchial stenosis

Mesh : Respiratory Physiological Phenomena Stents

来  源:   DOI:10.1016/j.resinv.2016.02.006   PDF(Sci-hub)

Abstract:
BACKGROUND: The point in the airway that allows the smallest maximal flow is known as the \"choke point\". The tube law describes the velocity of the expired air, which cannot exceed the wave-speed. Flow limitation during forced expiration is affected by the relationship between the transmural pressure (Ptm) and cross-sectional area (A) of the airway. Wave speed is dependent on the stiffness of the airway wall, as well as on the cross-section of the airway itself (dA/dPtm).
METHODS: Airway stenting at the wave-speed, flow-limiting segment (choke point) is assessed by using a catheter, via the working channel of a stereoscopic bronchoscope, to measure the difference between lateral pressure and pleural pressure.
RESULTS: Based on the wave-speed concept of maximal expiratory flow limitation, stenting at the choke point increased the cross-sectional area and supported the weakened airway wall, thus improving expiratory flow limitation and relieving dyspnea.
CONCLUSIONS: To ensure correct stent positioning and thus optimal functional benefit, it is important to locate the exact position of tracheobronchial stenosis.
摘要:
背景:气道中允许最小最大流量的点称为“阻塞点”。管道定律描述了呼出空气的速度,不能超过波速。强制呼气期间的流量限制受气道的跨壁压(Ptm)和横截面积(A)之间的关系影响。波速取决于气道壁的刚度,以及气道本身的横截面(dA/dPtm)。
方法:波速气道支架置入术,流量限制段(阻塞点)通过使用导管进行评估,通过立体支气管镜的工作通道,测量侧卧压和胸膜压之间的差异。
结果:基于最大呼气流量限制的波速概念,在阻塞点的支架增加了横截面积并支撑了弱化的气道壁,从而改善呼气流量限制和缓解呼吸困难。
结论:为了确保正确的支架定位,从而确保最佳的功能效益,准确定位气管支气管狭窄的位置非常重要。
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