关键词: Fungi Histology Hyperreflective lines In vitro cultivation Polymerase chain reaction

Mesh : Aged Diagnosis, Differential Diagnostic Techniques, Ophthalmological Eye Infections, Fungal / diagnostic imaging microbiology pathology Humans Keratitis / diagnostic imaging microbiology pathology Male Microscopy, Confocal / methods Middle Aged

来  源:   DOI:10.1007/s00347-015-0206-4   PDF(Sci-hub)

Abstract:
Fungal keratitis is a rare but very serious eye disease in industrial nations with a frequency of 1-5 % of all forms of keratitis from microbial causes. We present two patients with keratitis of primary unknown cause. Using confocal microscopy fungal filaments could be identified that partially showed a parallel configuration (like \"railway tracks\"). Thus, the correct diagnosis can often be made and suitable therapy can be non-invasively initiated even before the results of in vitro cultivation (fungal culture), polymerase chain reaction (PCR) and histological investigations are available.
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