Pyoderma gangrenosum, acne, suppurative hidradenitis (PASH) and polycystic ovary syndrome: Coincidentally or aetiologically connected?

坏疽性脓皮病,痤疮,化脓性汗腺炎 （ PASH ） 和多囊卵巢综合征 ： 巧合或病因学相关 ？

• 影响指数: 2.481
• 发表时间: May 2017
• 来源期刊: Australas J Dermatol
• DOI: 10.1111/ajd.12438
• PMID: 26831949
• 文章类型: Case Reports
• 中科院分区: Q3
• 方向: 医学
• 作者列表: Zivanovic D,Masirevic I,Ruzicka T,Braun-Falco M,Nikolic M

关键词: PCOS; PASH syndrome; autoinflammatory diseases; hidradenitis suppurativa; pyoderma gangrenosum

Mesh: Acne Vulgaris / complications; Adult; Female; Hidradenitis Suppurativa / complications; Humans; Polycystic Ovary Syndrome / complications; Pyoderma Gangrenosum / complications; Syndrome

Abstract

The clinical triad of pyoderma gangrenosum, acne conglobata and hidradenitis suppurativa has been named PASH syndrome. Polycystic ovary syndrome (PCOS) is associated with hyperandrogenism and inflammation. Hidradenitis suppurativa, like acne vulgaris, may be a feature of hyperandrogenism. Obesity may be associated with both hidradenitis suppurativa and PCOS. We describe a possible association between PASH syndrome and PCOS.

摘要

坏疽性脓皮病的临床三联征，痤疮并发和化脓性汗腺炎已被命名为PASH综合征。多囊卵巢综合征（PCOS）与高雄激素血症和炎症有关。化脓性汗腺炎,比如寻常痤疮,可能是高雄激素血症的一个特征。肥胖可能与化脓性汗腺炎和PCOS有关。我们描述了PASH综合征和PCOS之间可能的关联。