Mesh : Antineoplastic Combined Chemotherapy Protocols / therapeutic use Chemotherapy, Adjuvant Cyclin-Dependent Kinase 4 / metabolism Disease Management Humans Magnetic Resonance Imaging Neoadjuvant Therapy Positron Emission Tomography Computed Tomography Proto-Oncogene Proteins c-mdm2 / metabolism Radiotherapy Radiotherapy, Adjuvant Retroperitoneal Neoplasms / diagnostic imaging metabolism pathology therapy Sarcoma / diagnostic imaging metabolism pathology therapy Singapore Tomography, X-Ray Computed

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Abstract:
BACKGROUND: The SCAN sarcoma workgroup aimed to develop Singapore Cancer Network (SCAN) clinical practice guidelines for the initial evaluation, diagnosis and management of patients with retroperitoneal soft tissue sarcoma.
METHODS: The workgroup utilised a consensus approach to create high quality evidence-based clinical practice guidelines suited for our local setting.
RESULTS: Various international guidelines from the fields of radiology, pathology, surgical, medical and radiation oncology were reviewed. Recommendations on the role of radiological imaging, pathology, surgery, radiotherapy and systemic therapy in the management of retroperitoneal soft tissue sarcoma were developed.
CONCLUSIONS: These guidelines form the SCAN Guidelines 2015 for the diagnosis, staging and optimal management of patients with retroperitoneal soft tissue sarcoma.
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