关键词: Emmonsia HIV disseminated infection

Mesh : AIDS-Related Opportunistic Infections / diagnosis drug therapy microbiology Adult Amphotericin B / therapeutic use Antifungal Agents / therapeutic use Biopsy, Needle Chest Pain / microbiology Chrysosporium / classification genetics isolation & purification DNA, Fungal / isolation & purification DNA, Ribosomal / isolation & purification Diagnostic Errors Dyspnea / microbiology Female Humans India / epidemiology Itraconazole / therapeutic use Mycoses / diagnosis drug therapy microbiology Phylogeny Weight Loss

来  源:   DOI:10.1111/myc.12437

Abstract:
We report here the first case of disseminated Emmonsia pasteuriana infection in a patient with AIDS in India. The patient presented with weight loss, dyspnoea, left-sided chest pain and multiple non-tender skin lesions over face and body for 3 months. Disseminated emmonsiosis was diagnosed on microscopic examination and fungal culture of skin biopsy and needle aspirate of lung consolidation. It was confirmed by sequencing internal transcribed spacer region of rDNA, beta tubulin, actin, and intein PRP8. The patient responded to amphotericin B and itraconazole therapy.
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