PDF(Pubmed)
Abstract：
BACKGROUND: The aspiration for light skin (fair complexion) is becoming pronounced in a greater number of people in the present times with natural products being more in demand than their synthetic counterparts. Research in the area of skin-lightening agents is an expanding field with the knowledge being updated regularly. In Ayurveda, varṇya, raktaprasādana, tvacya are few terms specifying skin lightening with respect to its modern counterpart i.e., Tyrosinase inhibition, the most commonly reported method of skin lightening.
OBJECTIVE: The present review is undertaken for screening twenty herbs from Varṇya Mahākaṣāya, Lodhrādi varṇya gaṇa, Elādi varṇa prasādana gaṇa and few varṇya formulations to evaluate their probable modes of action through which the skin lightening is effected as per both Ayurveda and biomedical concepts.
METHODS: Critical review of herbs to show varṇya property is compiled from various Ayurvedic texts as well as from multiple articles on the internet to justify their skin lightening property on the basis of data collected.
CONCLUSIONS: All the twenty herbs reviewed are found to act as varṇya directly (citation as varṇya) or indirectly (alleviation of pitta and rakta) as per Ayurveda and to interfere in melanogenesis pathway through tyrosinase inhibition as per biomedicine. This shows their potential to act as good skin whitening agents. Śuṇṭhi being a part of many varṇya formulations, is the only herb among all reviewed in the present study found to exhibit tyrosinase inhibition without any Ayurvedic citation of varṇya property.
OBJECTIVE: The present review is undertaken for screening twenty herbs from Varṇya Mahākaṣāya, Lodhrādi varṇya gaṇa, Elādi varṇa prasādana gaṇa and few varṇya formulations to evaluate their probable modes of action through which the skin lightening is effected as per both Ayurveda and biomedical concepts.
METHODS: Critical review of herbs to show varṇya property is compiled from various Ayurvedic texts as well as from multiple articles on the internet to justify their skin lightening property on the basis of data collected.
CONCLUSIONS: All the twenty herbs reviewed are found to act as varṇya directly (citation as varṇya) or indirectly (alleviation of pitta and rakta) as per Ayurveda and to interfere in melanogenesis pathway through tyrosinase inhibition as per biomedicine. This shows their potential to act as good skin whitening agents. Śuṇṭhi being a part of many varṇya formulations, is the only herb among all reviewed in the present study found to exhibit tyrosinase inhibition without any Ayurvedic citation of varṇya property.
摘要：
背景：目前，越来越多的人对浅色皮肤（白皙肤色）的渴望变得越来越明显，天然产品的需求量比合成产品的需求量更大。皮肤增亮剂领域的研究是一个不断扩展的领域，知识会定期更新。在阿育吠陀,瓦尔雅,raktaprasādana,tvacya是很少的术语，相对于其现代对应物，酪氨酸酶抑制，最常报道的美白方法。
目的：本综述是为了筛选来自VarñyaMahākaāya的二十种草药，Lodhrādivar_ya_ga_a,按照阿育吠陀和生物医学概念，评估其可能的作用方式，通过这种作用方式可以实现皮肤美白。
方法：根据收集的数据，从各种阿育吠陀文本以及互联网上的多篇文章中汇编了对草药的批判性审查，以显示其皮肤美白特性。
结论：根据阿育吠陀，所有20种草药都被发现直接（引用为va）或间接（减轻pitta和rakta）起作用，并通过酪氨酸酶抑制干扰黑素生成途径。根据生物医学。这显示了它们作为良好的皮肤增白剂的潜力。作为许多变种配方的一部分，是本研究中所有综述中发现的唯一一种具有酪氨酸酶抑制作用的草药，而没有任何阿育吠陀引用的变种特性。
目的：本综述是为了筛选来自VarñyaMahākaāya的二十种草药，Lodhrādivar_ya_ga_a,按照阿育吠陀和生物医学概念，评估其可能的作用方式，通过这种作用方式可以实现皮肤美白。
方法：根据收集的数据，从各种阿育吠陀文本以及互联网上的多篇文章中汇编了对草药的批判性审查，以显示其皮肤美白特性。
结论：根据阿育吠陀，所有20种草药都被发现直接（引用为va）或间接（减轻pitta和rakta）起作用，并通过酪氨酸酶抑制干扰黑素生成途径。根据生物医学。这显示了它们作为良好的皮肤增白剂的潜力。作为许多变种配方的一部分，是本研究中所有综述中发现的唯一一种具有酪氨酸酶抑制作用的草药，而没有任何阿育吠陀引用的变种特性。
