Abstract：
OBJECTIVE: This study aims to evaluate the clinical outcomes of transcatheter thrombolysis in acute superior mesenteric venous thrombosis (ASMVT) associated with bowel necrosis.
METHODS: A retrospective study of six patients with ASMVT treated with catheter-directed thrombectomy/thrombolysis and damage control surgery at Jinling Hospital (Nanjing, China) between 2010 and 2013 was conducted. Demographics, past medical history, risk factors, therapeutic methods and effects, mortality, and follow-up of the study population were assessed.
RESULTS: Five of six patients underwent arteriovenous combined thrombolysis, while one patient underwent arterial thrombolysis. All patients required damage control surgery, and four of these patients underwent temporary abdominal closure. All patients survived and were free of recurrence.
CONCLUSIONS: Transcatheter thrombectomy/thrombolysis and damage control surgery could help avoid extensive bowel resection, prevent short bowel syndrome and reduce mortality for critically ill patients with acute mesenteric venous thrombosis associated with bowel necrosis.
METHODS: A retrospective study of six patients with ASMVT treated with catheter-directed thrombectomy/thrombolysis and damage control surgery at Jinling Hospital (Nanjing, China) between 2010 and 2013 was conducted. Demographics, past medical history, risk factors, therapeutic methods and effects, mortality, and follow-up of the study population were assessed.
RESULTS: Five of six patients underwent arteriovenous combined thrombolysis, while one patient underwent arterial thrombolysis. All patients required damage control surgery, and four of these patients underwent temporary abdominal closure. All patients survived and were free of recurrence.
CONCLUSIONS: Transcatheter thrombectomy/thrombolysis and damage control surgery could help avoid extensive bowel resection, prevent short bowel syndrome and reduce mortality for critically ill patients with acute mesenteric venous thrombosis associated with bowel necrosis.
摘要：
目的：本研究旨在评估经导管溶栓治疗与肠坏死相关的急性肠系膜上静脉血栓形成（ASMVT）的临床效果。
方法：对金陵医院6例接受导管定向取栓/溶栓和损伤控制手术治疗的ASMVT患者进行回顾性研究（南京，中国）在2010年至2013年之间进行了。人口统计,既往病史,危险因素，治疗方法和效果，死亡率,并对研究人群的随访情况进行了评估。
结果：6例患者中有5例接受了动静脉联合溶栓，1例患者接受动脉溶栓治疗。所有患者都需要进行损伤控制手术,其中四名患者接受了临时腹部关闭。所有患者均存活且无复发。
结论：经导管取栓/溶栓和损伤控制性手术有助于避免广泛的肠切除，急性肠系膜静脉血栓形成伴肠坏死的危重患者可预防短肠综合征并降低死亡率。
方法：对金陵医院6例接受导管定向取栓/溶栓和损伤控制手术治疗的ASMVT患者进行回顾性研究（南京，中国）在2010年至2013年之间进行了。人口统计,既往病史,危险因素，治疗方法和效果，死亡率,并对研究人群的随访情况进行了评估。
结果：6例患者中有5例接受了动静脉联合溶栓，1例患者接受动脉溶栓治疗。所有患者都需要进行损伤控制手术,其中四名患者接受了临时腹部关闭。所有患者均存活且无复发。
结论：经导管取栓/溶栓和损伤控制性手术有助于避免广泛的肠切除，急性肠系膜静脉血栓形成伴肠坏死的危重患者可预防短肠综合征并降低死亡率。
