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Abstract：
Endobronchial metastasis is a rare manifestation of differentiated thyroid cancer. A 79-year-old male was admitted to the hospital with shortness of breath, chest pain, anemia, and weight loss. Computed tomography of chest revealed multiple lung nodules. Bronchoscopy showed an endobronchial lesion in the right upper lobe. The biopsy of the lesion demonstrated neoplastic cells stained positive for thyroglobulin, thyroid transcription factor-1, and cytokeratin-7, consistent with metastatic follicular thyroid cancer. Physical examination revealed a firm fixed thyroid nodule, which was confirmed by thyroid ultrasound. He subsequently underwent total thyroidectomy and neck exploration. Thyroid gland pathology revealed a nodule with features of high-grade follicular thyroid carcinoma. Metastatic thyroid cancer should be considered in workup of pulmonary nodules. We recommend an examination of thyroid gland in patients who present with pulmonary nodules associated with signs and symptoms of malignancy.
摘要：
支气管内转移是分化型甲状腺癌的罕见表现。一名79岁男性因呼吸急促入院,胸痛,贫血,和减肥。胸部计算机断层扫描显示多个肺结节。支气管镜检查显示右上叶支气管内病变。病灶活检显示肿瘤细胞甲状腺球蛋白染色阳性，甲状腺转录因子-1和细胞角蛋白-7与转移性滤泡性甲状腺癌一致。体格检查发现有一个固定的甲状腺结节,甲状腺超声证实了这一点。随后，他接受了全甲状腺切除术和颈部探查。甲状腺病理显示结节，具有高度滤泡性甲状腺癌的特征。在肺结节的检查中应考虑转移性甲状腺癌。我们建议对存在与恶性肿瘤体征和症状相关的肺结节的患者进行甲状腺检查。
