关键词: Cardiovascular risk anemia dialysate calcium dyslipidemia glycosylated hemoglobin hypertension hypokalemia inflammation obesity peritoneal dialysis residual renal function salt volume

Mesh : Adult Cardiovascular Diseases / etiology therapy Disease Management Female Humans Male Metabolic Diseases / etiology therapy Patient Safety Peritoneal Dialysis / adverse effects standards Practice Guidelines as Topic Risk Assessment Societies, Medical Treatment Outcome

来  源:   DOI:10.3747/pdi.2014.00279   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Cardiovascular disease contributes significantly to the adverse clinical outcomes of peritoneal dialysis (PD) patients. Numerous cardiovascular risk factors play important roles in the development of various cardiovascular complications. Of these, loss of residual renal function is regarded as one of the key cardiovascular risk factors and is associated with an increased mortality and cardiovascular death. It is also recognized that PD solutions may incur significant adverse metabolic effects in PD patients. The International Society for Peritoneal Dialysis (ISPD) commissioned a global workgroup in 2012 to formulate a series of recommendations regarding lifestyle modification, assessment and management of various cardiovascular risk factors, as well as management of the various cardiovascular complications including coronary artery disease, heart failure, arrhythmia (specifically atrial fibrillation), cerebrovascular disease, peripheral arterial disease and sudden cardiac death, to be published in 2 guideline documents. This publication forms the first part of the guideline documents and includes recommendations on assessment and management of various cardiovascular risk factors. The documents are intended to serve as a global clinical practice guideline for clinicians who look after PD patients. The ISPD workgroup also identifies areas where evidence is lacking and further research is needed.
摘要:
心血管疾病对腹膜透析(PD)患者的不良临床结局有重要贡献。许多心血管危险因素在各种心血管并发症的发生发展中起重要作用。其中,残余肾功能的丧失被认为是心血管疾病的关键危险因素之一,并与死亡率和心血管死亡的增加有关。还认识到,PD溶液可能在PD患者中引起显著的不良代谢作用。国际腹膜透析学会(ISPD)于2012年委托一个全球工作组制定了一系列关于改变生活方式的建议,各种心血管危险因素的评估和管理,以及各种心血管并发症的管理,包括冠状动脉疾病,心力衰竭,心律失常(特别是心房颤动),脑血管疾病,外周动脉疾病和心脏性猝死,将在2个指南文件中发布。本出版物是指南文件的第一部分,包括各种心血管危险因素的评估和管理建议。这些文件旨在为照顾PD患者的临床医生提供全球临床实践指南。ISPD工作组还确定了缺乏证据的领域,需要进一步研究。
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