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Abstract：
Trichophyton erinacei is a zoonotic fungus affecting hedgehogs. Although several human infections with this organism have been documented in the literature, it has rarely been isolated as a human pathogen. This paper reports on an erythematous lesion spotted on the hand of a 10-year-old girl. Based on the culture of the patient\'s skin scrapings, the pathogen was mycologically identified as T. erinacei, which was further confirmed by sequencing the internal transcribed spacers of the fungal nuclear ribosomal DNA using universal primer ITS1-ITS4. This is the first case of T. erinacei in a Tunisian patient. A survey was carried out on the environment of our patient, and the results revealed the presence of hedgehogs with suspect scaly lesions. The same fungus was isolated from the hair and scales of the hedgehog, which was confirmed by PCR sequencing. The frequency of T. erinacei has often been underestimated, which is attributed not only to the gaps of knowledge still existing in the current understanding of the dermatophyte but also to differential diagnosis problems. Molecular study offers a simple and rapid tool to identify the source of infection and, hence, avoid the risk of recurrence.
摘要：
毛癣菌是一种影响刺猬的人畜共患真菌。尽管文献中已经记录了这种生物的几种人类感染，它很少被分离为人类病原体。本文报道了一个10岁女孩手上发现的红斑病变。根据患者皮肤刮片的培养，病原体在真菌学上被鉴定为木耳弧菌，通过使用通用引物ITS1-ITS4对真菌核核糖体DNA的内部转录间隔区进行测序进一步证实了这一点。这是突尼斯患者中的第一例赤霉病。对我们病人的环境进行了调查，结果显示有刺猬有可疑的鳞状病变。从刺猬的头发和鳞片中分离出相同的真菌，通过PCR测序证实。鸡毛蒜皮的频率经常被低估，这不仅归因于目前对皮肤癣菌的理解中仍然存在的知识空白，还归因于鉴别诊断问题。分子研究提供了一种简单快速的工具来确定感染源，因此，避免复发的风险。
