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Abstract：
OBJECTIVE: Liver-specific MRI is a fast-growing field, with technological and protocol advancements providing more robust imaging and allowing a greater depth of information per examination. This article reports the evidence for, and expert thinking on, current challenges in liver-specific MRI, as discussed at the 7th International Forum for Liver MRI, which was held in Shanghai, China, in October 2013.
METHODS: Topics discussed included the role of gadoxetic acid-enhanced MRI in the differentiation of focal nodular hyperplasia from hepatocellular adenoma and small hepatocellular carcinoma (HCC) from small intrahepatic cholangiocarcinoma (in patients with chronic liver disease), the differentiation of low-grade dysplastic nodule (DN) from pre-malignant high-grade DN and early HCC, and treatment planning and assessment of treatment response for patients with HCC and colorectal liver metastasis. Optimization of the gadoxetic acid-enhanced MRI protocol to gain robust arterial and hepatobiliary phase images was also discussed.
CONCLUSIONS: Gadoxetic acid-enhanced MRI demonstrates added value for the detection and characterization of focal liver lesions and shows promise in a number of new indications, including regional liver functional assessment and patient monitoring after therapy; however, more data are needed in some areas, and further developments are needed to translate cutting-edge techniques into clinical practice.
CONCLUSIONS: Liver-specific MRI is a fast-growing field, with many technological and protocol advancements. Gadoxetic acid-enhanced MRI demonstrates value for detecting and characterizing focal liver lesions. Gadoxetic acid-enhanced MRI shows promise in regional functional assessment and patient monitoring. Further developments are needed to translate cutting-edge techniques into clinical practice.
METHODS: Topics discussed included the role of gadoxetic acid-enhanced MRI in the differentiation of focal nodular hyperplasia from hepatocellular adenoma and small hepatocellular carcinoma (HCC) from small intrahepatic cholangiocarcinoma (in patients with chronic liver disease), the differentiation of low-grade dysplastic nodule (DN) from pre-malignant high-grade DN and early HCC, and treatment planning and assessment of treatment response for patients with HCC and colorectal liver metastasis. Optimization of the gadoxetic acid-enhanced MRI protocol to gain robust arterial and hepatobiliary phase images was also discussed.
CONCLUSIONS: Gadoxetic acid-enhanced MRI demonstrates added value for the detection and characterization of focal liver lesions and shows promise in a number of new indications, including regional liver functional assessment and patient monitoring after therapy; however, more data are needed in some areas, and further developments are needed to translate cutting-edge techniques into clinical practice.
CONCLUSIONS: Liver-specific MRI is a fast-growing field, with many technological and protocol advancements. Gadoxetic acid-enhanced MRI demonstrates value for detecting and characterizing focal liver lesions. Gadoxetic acid-enhanced MRI shows promise in regional functional assessment and patient monitoring. Further developments are needed to translate cutting-edge techniques into clinical practice.
摘要：
目的：肝脏特异性MRI是一个快速发展的领域，随着技术和协议的进步，提供了更强大的成像，并允许每次检查更深入的信息。这篇文章报道了证据，和专家思考，肝脏特异性MRI的当前挑战，正如在第七届国际肝脏MRI论坛上讨论的那样，在上海举行，中国,2013年10月。
方法：讨论的主题包括gadoxetic酸增强MRI在区分局灶性结节增生与肝细胞腺瘤和小肝细胞癌（HCC）与小肝内胆管癌（慢性肝病患者）中的作用。低度发育不良结节（DN）与癌前高级别DN和早期HCC的区别，以及HCC和结直肠肝转移患者的治疗计划和治疗反应评估。还讨论了优化gadoxetic酸增强的MRI方案以获得强大的动脉和肝胆相图像。
结论：加多塞酸增强MRI显示了对肝脏局灶性病变的检测和表征的附加价值，并在许多新的适应症中显示出希望，包括区域肝功能评估和治疗后的患者监测;然而，在某些领域需要更多的数据，需要进一步的发展将尖端技术转化为临床实践。
结论：肝脏特异性MRI是一个快速发展的领域，随着许多技术和协议的进步。Gadoxetic酸增强MRI显示了检测和表征局灶性肝脏病变的价值。盐酸增强MRI在区域功能评估和患者监测中显示出希望。需要进一步的发展将尖端技术转化为临床实践。
方法：讨论的主题包括gadoxetic酸增强MRI在区分局灶性结节增生与肝细胞腺瘤和小肝细胞癌（HCC）与小肝内胆管癌（慢性肝病患者）中的作用。低度发育不良结节（DN）与癌前高级别DN和早期HCC的区别，以及HCC和结直肠肝转移患者的治疗计划和治疗反应评估。还讨论了优化gadoxetic酸增强的MRI方案以获得强大的动脉和肝胆相图像。
结论：加多塞酸增强MRI显示了对肝脏局灶性病变的检测和表征的附加价值，并在许多新的适应症中显示出希望，包括区域肝功能评估和治疗后的患者监测;然而，在某些领域需要更多的数据，需要进一步的发展将尖端技术转化为临床实践。
结论：肝脏特异性MRI是一个快速发展的领域，随着许多技术和协议的进步。Gadoxetic酸增强MRI显示了检测和表征局灶性肝脏病变的价值。盐酸增强MRI在区域功能评估和患者监测中显示出希望。需要进一步的发展将尖端技术转化为临床实践。
