FBXO4 损失促进致癌物诱导小鼠乳头状瘤的发展。
关键词: BrdU, Bromodeoxyuridine CDK, Cyclin Dependent Kinase CDK4 DMSO, Dimethyl Sulfoxide EGFR, Epidermal Growth Factor Receptor ESCC ESCC, Esophageal Squamous Cell Carcinoma FBXO4 FBXO4, F box only protein 4 GI, Gastrointestinal tract H&E, Hematoxylin and Eosin Het, Heterozygous NMBA, N-nitrosomethylbenzylamine PBS, Phosphate Buffered Saline PD0332991 PE, Preneoplastic Esophagus PI, Propidium Iodide Rb, Retinoblastoma Protein SCC, Squamous Cell Carcinoma SCF, Skp1-Cul1-F box protein TNFa, Tumor Necrosis Factor alpha Wt, Wild Type cyclin D1
Mesh : Animals Carcinoma, Squamous Cell / genetics pathology therapy Cyclin D1 / genetics Esophageal Neoplasms / genetics pathology therapy Esophageal Squamous Cell Carcinoma F-Box Proteins / genetics metabolism Humans Mice Mutation
来 源: DOI:10.1080/15384047.2015.1026512