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Abstract：
OBJECTIVE: The correlated analysis and pathological study on insulin resistance and cardiovascular endocrine hormone in elderly hypertension patients was investigated by clinical observation and physical experiments in my hospital.
METHODS: Randomly enrolled 300 subjects seen at hospital from January 2011 to January 2013, which included 150 hypertension patients and 150 non-hypertension of healthy people, while 150 cases of hypertension patients as the experimental group, 150 cases of healthy people without hypertension acts as the control group. The t-PA of serum (plasma), activity of PAI, ANP, IS, ET were determined in this 300 subjects, and it studied on the correlation and pathological effect between insulin resistance and cardiovascular endocrine hormone in elderly hypertension patients.
RESULTS: The levels of PAI, ANP, ET are apparently higher in hypertension patients than in healthy control group (p<0.05), while the t-PA, IS are obviously lower in hypertensive patients than in healthy control group (p>0.05).
CONCLUSIONS: This study has shown that there is a significant correlation and pathological effect between insulin resistance and cardiovascular endocrine hormone in hypertensive patients, and which plays an important role in genesis and development of hypertension in elderly people.
METHODS: Randomly enrolled 300 subjects seen at hospital from January 2011 to January 2013, which included 150 hypertension patients and 150 non-hypertension of healthy people, while 150 cases of hypertension patients as the experimental group, 150 cases of healthy people without hypertension acts as the control group. The t-PA of serum (plasma), activity of PAI, ANP, IS, ET were determined in this 300 subjects, and it studied on the correlation and pathological effect between insulin resistance and cardiovascular endocrine hormone in elderly hypertension patients.
RESULTS: The levels of PAI, ANP, ET are apparently higher in hypertension patients than in healthy control group (p<0.05), while the t-PA, IS are obviously lower in hypertensive patients than in healthy control group (p>0.05).
CONCLUSIONS: This study has shown that there is a significant correlation and pathological effect between insulin resistance and cardiovascular endocrine hormone in hypertensive patients, and which plays an important role in genesis and development of hypertension in elderly people.
摘要：
目的：通过临床观察和物理实验，对老年高血压患者胰岛素抵抗与心血管内分泌激素的相关性分析和病理研究进行探讨。
方法：随机抽取了2011年1月至2013年1月在医院就诊的300名受试者，其中包括150名高血压患者和150名非高血压健康人。150例高血压患者作为实验组,以150例没有高血压的健康人作为对照组。血清（血浆）的t-PA，PAI的活动，ANP,IS,在这300名受试者中测定了ET，探讨老年高血压患者胰岛素抵抗与心血管内分泌激素的相关性及病理效应。
结果：PAI的水平，ANP,高血压患者的ET明显高于健康对照组（p<0.05）。而T-PA,高血压患者的IS明显低于健康对照组（p>0.05）。
结论：本研究表明，高血压患者胰岛素抵抗与心血管内分泌激素之间存在显著的相关性和病理效应。在老年人高血压的发生和发展中起着重要作用。
方法：随机抽取了2011年1月至2013年1月在医院就诊的300名受试者，其中包括150名高血压患者和150名非高血压健康人。150例高血压患者作为实验组,以150例没有高血压的健康人作为对照组。血清（血浆）的t-PA，PAI的活动，ANP,IS,在这300名受试者中测定了ET，探讨老年高血压患者胰岛素抵抗与心血管内分泌激素的相关性及病理效应。
结果：PAI的水平，ANP,高血压患者的ET明显高于健康对照组（p<0.05）。而T-PA,高血压患者的IS明显低于健康对照组（p>0.05）。
结论：本研究表明，高血压患者胰岛素抵抗与心血管内分泌激素之间存在显著的相关性和病理效应。在老年人高血压的发生和发展中起着重要作用。
