关键词: ACT, activated clotting time ALF ALF, acute liver failure APTT, activated partial thromboplastin time ARDS, acute respiratory distress syndrome CCO, continuous CO CCTs, conventional coagulation tests CI, cardiac index CL, clot lysis CO, cardiac output CR, clot rate CVP, central venous pressure ESLD, end stage liver disease EVLWI, extra vascular lung water index ICG, indocyanine green ICH, intracranial hypertension ICP, intracranial pressure LT, liver transplant MA, maximum amplitude ONSD, optic nerve sheath diameter PAC, pulmonary artery catheter PAOP, pulmonary arterial occlusion pressure PF, platelet function PI, pulsatility index PT, prothrombin time ROTEM, rotation thrombelastometry RVEDV, right ventricular end-diastolic volume SV, stroke volume SVR, systemic vascular resistance TCD, transcranial Doppler TDCO, thermodilution principle TEE, transesophageal echocardiography TEG, thrombelastography cirrhosis coagulopathy intracranial pressure monitoring liver transplant mPAP, mean pulmonary artery pressure

来  源:   DOI:10.1016/j.jceh.2012.06.003   PDF(Sci-hub)

Abstract:
Liver transplant (LT) is a major surgical undertaking involving major fluid shifts, hemodynamic instability and metabolic derangements in a patient with preexisting liver failure and multisystemic derangements. Monitoring and organ support initiated in the preoperative phase is continued intraoperatively and into the postoperative phase to ensure an optimal outcome. As cardiovascular events are the leading cause of non-graft related death among LT recipients, major emphasis is placed on cardiovascular monitoring. The other essential monitoring are the continuous assessment of coagulapathy, extent of metabolic derangements, dyselectrolytemis and intracranial pressure monitoring in patients with fulminant hepatic failure. The type and extent of monitoring differs with need according to preexisting child status of the patient and the extent of systemic derangements. It also varies among transplant centers and is mainly determined by individual or institutional practices.
摘要:
肝移植(LT)是一项涉及重大液体转移的重大外科手术,先前存在肝功能衰竭和多系统紊乱的患者的血流动力学不稳定和代谢紊乱。在术前阶段开始的监测和器官支持在术中和术后阶段继续进行,以确保最佳结果。由于心血管事件是LT受者非移植物相关死亡的主要原因,重点放在心血管监测。其他必要的监测是对凝血病的持续评估,代谢紊乱的程度,暴发性肝衰竭患者的电解质紊乱和颅内压监测。根据患者先前存在的儿童状况和全身紊乱的程度,监测的类型和程度因需要而异。它也因移植中心而异,主要取决于个人或机构的做法。
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