Abstract：
A heterozygosity-fitness correlations (HFCs) may reflect inbreeding depression, but the extent to which they do so is debated. HFCs are particularly likely to occur after demographic disturbances such as population bottleneck or admixture. We here study HFC in an introduced and isolated ungulate population of white-tailed deer Odocoileus virginianus in Finland founded in 1934 by four individuals. A total of 422 ≥ 1-year-old white-tailed deer were collected in the 2012 hunting season in southern Finland and genotyped for 14 microsatellite loci. We find significant identity disequilibrium as estimated by g 2. Heterozygosity was positively associated with size- and age-corrected body mass, but not with jaw size or (in males) antler score. Because of the relatively high identity disequilibrium, heterozygosity of the marker panel explained 51% of variation in inbreeding. Inbreeding explained approximately 4% of the variation in body mass and is thus a minor, although significant source of variation in body mass in this population. The study of HFC is attractive for game- and conservation-oriented wildlife management because it presents an affordable and readily used approach for genetic monitoring that allowing identification of fitness costs associated with genetic substructuring in what may seem like a homogeneous population.
摘要：
杂合性-适应性相关性(HFCs)可能反映近交抑郁，但是他们这样做的程度是有争议的。氢氟碳化合物特别有可能发生在诸如人口瓶颈或混合等人口结构紊乱之后。我们在这里研究了1934年由四个人在芬兰成立的白尾鹿Odocoileusvirginianus引入和分离的有蹄类动物种群中的HFC。在2012年芬兰南部的狩猎季节，共收集了422头≥1岁的白尾鹿，并对其进行了14个微卫星基因座的基因分型。我们发现由g2估计的显著身份不平衡。杂合性与大小和年龄校正后的体重呈正相关，但不与下巴大小或（在男性）鹿角得分。由于身份不平衡相对较高，标记组的杂合性解释了近交中51%的变异。近亲繁殖解释了大约4％的体重变化，因此是次要的，尽管该人群中体重变化的重要来源。HFC的研究对于以游戏和保护为导向的野生动植物管理具有吸引力，因为它提供了一种负担得起且易于使用的遗传监测方法，可以识别与似乎是同质种群的遗传亚结构相关的健身成本。
