从结鞘叶中分离的硫酸多糖天冬多糖对 B16 黑色素瘤的抗转移作用。
关键词: Ascophyllan Ascophyllum nodosum B16 melanoma Melanoma metastasis Sulfated polysaccharide
Mesh : Adjuvants, Immunologic / chemistry therapeutic use Animals Anticarcinogenic Agents / chemistry therapeutic use Ascophyllum / chemistry Cell Line, Tumor Killer Cells, Natural / drug effects immunology Lung / drug effects immunology metabolism pathology Lung Neoplasms / immunology metabolism prevention & control secondary MAP Kinase Signaling System / drug effects Male Matrix Metalloproteinase 9 / metabolism Melanoma, Experimental / drug therapy immunology metabolism pathology Mice Mice, Inbred C57BL Neoplasm Invasiveness / immunology pathology prevention & control Polysaccharides / chemistry therapeutic use Spleen / cytology
来 源:
DOI:10.1016/j.bbrc.2015.01.061
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