关键词: Dendritic fibromyxolipoma fibrous papule myxoid liposarcoma solitary fibrous tumor spindle cell lipoma

Mesh : Aged Biomarkers, Tumor / analysis Biopsy Diagnosis, Differential Fibroma / chemistry pathology surgery Humans Immunohistochemistry Lipoma / chemistry pathology surgery Male Nose Neoplasms / chemistry pathology surgery Predictive Value of Tests

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Abstract:
Dendritic myxofibrolipoma is a newly described benign soft tissue tumor that could be easily mistaken for sarcoma. It develops primarily in the subcutis or muscular fascia of the head and neck, shoulders, etc. Histologically, the tumor is characterized by an admixture of mature adipose tissue, spindle and stellate cells, and abundant myxoid stroma with prominent collagenization. These neoplasms typically show positive immunoreactivity for CD-34, vimentin and Bcl-2. Herein, we described a rare case presenting with a papule on the nasal tip in a 69-year old patient. Histopathology and immunohistochemical staining confirmed the diagnosis. In short, it brings the attention of clinicians to the importance of proper identification and characterization of this tumor.
摘要:
树突状粘液纤维脂肪瘤是一种新描述的良性软组织肿瘤,很容易被误认为是肉瘤。它主要在头颈部的皮下组织或肌肉筋膜中发展,肩膀,等。组织学上,肿瘤的特征是成熟脂肪组织的混合物,梭形和星状细胞,和丰富的粘液样基质,胶原化突出。这些肿瘤通常对CD-34,波形蛋白和Bcl-2显示出阳性的免疫反应性。在这里,我们描述了一名69岁患者的罕见病例,其鼻尖上有丘疹。组织病理学和免疫组织化学染色证实了诊断。总之,它引起了临床医生的注意,正确识别和表征这种肿瘤的重要性。
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