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Abstract：
Sex cord stromal tumors (SCST) are rare cancers of the ovarian area in adults. They constitute a heterogeneous group of tumors that develop from the sex cords and the ovarian stroma. These tumors are detected typically at an early stage, and they may recur as late as 30 years after the initial treatment. Because 70% of the patients present with stage I tumors, surgery represents the most important therapeutic arm. There are no data to support any kind of postoperative adjuvant treatment for patients with stage IA or IB SCSTs, given the indolent nature of these neoplasms and the overall good prognosis. The long natural history of the disease may lead to repeated surgical procedure should a relapse occurs. Platinum-based chemotherapy is currently used for patients with advanced stage SCSTs or recurrent disease, with an overall response rate of 63% to 80%. The indolent nature of SCSTs with the tendency for late recurrence requires long-term follow-up.
摘要：
性索间质肿瘤（SCST）是成人卵巢区域的罕见癌症。它们构成了一组异质性肿瘤，从性索和卵巢基质发展而来。这些肿瘤通常在早期被发现，它们可能会在最初治疗后30年内复发。因为70%的患者出现I期肿瘤，手术是最重要的治疗手段。没有数据支持IA或IB期SCST患者的任何类型的术后辅助治疗，鉴于这些肿瘤的惰性性质和总体预后良好。如果复发，该疾病的长期自然史可能导致重复的外科手术。基于铂的化疗目前用于晚期SCSTs或复发性疾病的患者，总反应率为63%至80%。SCSTs的惰性性质具有晚期复发的趋势，需要长期随访。
