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Abstract：
Lobomycosis is a subcutaneous mycosis of chronic evolution caused by the Lacazia loboi fungus. Its distribution is almost exclusive in the Americas, and it has a particularly high prevalence in the Amazon basin. Cases of lobomycosis have been reported only in dolphins and humans. Its prevalence is higher among men who are active in the forest, such as rubber tappers, bushmen, miners, and Indian men. It is recognized that the traumatic implantation of the fungus on the skin is the route by which humans acquire this infection. The lesions affect mainly exposed areas such as the auricles and upper and lower limbs and are typically presented as keloid-like lesions. Currently, surgical removal is the therapeutic procedure of choice in initial cases. Despite the existing data and studies to date, the active immune mechanisms in this infection and its involvement in the control or development of lacaziosis have not been fully clarified. In recent years, little progress has been made in the appraisal of the epidemiologic aspects of the disease. So far, we have neither a population-based study nor any evaluation directed to the forest workers.
摘要：
Lobomcosis是由Lacazialoboi真菌引起的慢性发展的皮下真菌病。它的分布在美洲几乎是独家的，它在亚马逊河流域的患病率特别高。仅在海豚和人类中报道了小叶真菌病的病例。在森林中活跃的男性中，其患病率更高，如橡胶攻丝器，布希曼人,矿工,印度男人人们认识到，真菌在皮肤上的创伤性植入是人类获得这种感染的途径。病变主要影响外露区域，如耳廓和上肢和下肢，通常表现为瘢痕疙瘩样病变。目前,手术切除是最初病例的首选治疗方法。尽管迄今为止有现有的数据和研究，这种感染中的主动免疫机制及其在控制或发展中的作用尚未完全阐明。近年来,在评估该疾病的流行病学方面进展甚微。到目前为止,我们既没有基于人口的研究，也没有针对森林工人的任何评估。
