Mesh : Adult Allergens / adverse effects immunology Anaphylaxis / diagnosis etiology immunology Basophil Degranulation Test Bread / adverse effects analysis Female Flax / adverse effects immunology Food Hypersensitivity / diagnosis etiology immunology Histamine Release / immunology Humans Immunoglobulin E / immunology Skin Tests

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Abstract:
We recently experienced a 29-year-old female with anaphylaxis caused by linseed included in homemade bread. This is the first report of linseed-induced allergy in Japan. She obtained the linseed-containing ingredients of bread by mail order. We performed skin-prick tests and basophil degranulation tests using extracts of the ingredients and commercially available linseeds; both tests showed positive results for linseed. The patient\'s serum was also positive for linseed-specific IgE. Since linseeds are included in various kinds of foods and exposure to them is increasing, linseeds may need to be recognized as a potential trigger of immediate-type allergy in Japan.
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