在小鼠模型中 , 基质金属蛋白酶 9 的遗传去除挽救了脆性 X 综合征的症状。
关键词: dendritic spines extracellular matrix fragile X syndrome hippocampus mTOR signaling matrix metalloproteinase
Mesh : Animals Animals, Newborn Cells, Cultured Disease Models, Animal Fragile X Syndrome / genetics metabolism pathology Male Matrix Metalloproteinase 9 / deficiency genetics Mice Mice, 129 Strain Mice, Knockout Phenotype
来 源:
DOI:10.1523/JNEUROSCI.1162-14.2014
PDF(Sci-hub)