关键词: Dowling Degos disease Haber's syndrome reticulate acropigmentation of Dohi reticulate acropigmentation of Kitamura reticulate pigmentation

来  源:   DOI:10.4103/0019-5154.131408

Abstract:
Reticulate hyperpigmentary disorders are a group of rare genetic pigmentary abnormalities which includes reticulate acropigmentation of Kitamura (RAPK), Dowling-Degos disease (DD), reticulate acropigmentation of Dohi (RAPD), Haber\'s syndrome, and Galli-Galli disease. A 25-year-old male presented with asymptomatic dark-colored lesions on his hands and feet with light-colored skin lesions involving the trunk since three years. Dermatological examination revealed hyperpigmented macules in a reticulate pattern involving the dorsa of the hands and feet, front and sides of the neck, axillae, periorbital region, and groin. Multiple pits were present over both palms, with breaks in dermatoglyphics. He also had multiple nonacne facial scars predominantly on the nose and malar areas. The patient had overlapping features of RAPK and DDD. In addition, he also had hypopigmented macules and acneiform facial scars. Such an overlap of features of reticulate pigmentation has not been previously reported in the literature.
摘要:
网状色素沉着障碍是一组罕见的遗传性色素异常,包括北村的网状色素沉着(RAPK),道林-德戈斯病(DD),多希网状色素沉着(RAPD),哈伯综合征,和Galli-Galli病.一名25岁的男性,自三年以来,他的手和脚上出现无症状的深色病变,涉及躯干的浅色皮肤病变。皮肤病学检查显示,涉及手足背的网状色素沉着斑,颈部的正面和侧面,腋窝,眶周区,还有腹股沟.两个手掌上都有多个凹坑,皮肤象形文字中断。他还主要在鼻子和黄斑区域有多个非痤疮面部疤痕。患者具有RPK和DDD的重叠特征。此外,他也有色素沉着斑和痤疮样面部疤痕。这种网状色素沉着特征的重叠以前在文献中没有报道过。
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