关键词: Antimicrobial proteins Defensins Host defence LL-37 Neonate

Mesh : Antimicrobial Cationic Peptides / physiology Female Fetus / immunology Humans Immunity, Innate Infant, Newborn / immunology Infant, Newborn, Diseases / immunology Postpartum Period Pregnancy

来  源:   DOI:10.1111/apa.12700   PDF(Sci-hub)

Abstract:
At birth, the foetus makes the transition from the uterus to a world full of microbes. The newborn baby needs protection against potential invading pathogens and needs to establish a normal microbiota.
CONCLUSIONS: Antimicrobial peptides and proteins are key effector molecules of innate immunity and are also important immunomodulators. Their presence in the cells and tissues of the uterus, foetus and the neonate indicates an important role in immunity during pregnancy and in early life.
摘要:
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