低密度脂蛋白受体相关蛋白 - 1 : 在血管完整性调节中的作用。
关键词: LRP1 aneurysm elastin extracellular matrix fVIII
Mesh : Aneurysm / prevention & control Animals Atherosclerosis / metabolism Blood Coagulation / physiology Elastin / metabolism Endocytosis / physiology Extracellular Matrix / metabolism Factor VIII / metabolism Humans Lipoproteins, LDL / metabolism Liver / metabolism Low Density Lipoprotein Receptor-Related Protein-1 / chemistry physiology Macrophages / metabolism Mice Mice, Knockout Models, Animal Models, Molecular Muscle, Smooth, Vascular / metabolism Organ Specificity Peptide Hydrolases / metabolism Platelet-Derived Growth Factor / metabolism Protein Conformation Receptors, LDL / deficiency genetics physiology Signal Transduction Thromboplastin / metabolism Transforming Growth Factor beta / physiology Tumor Suppressor Proteins / deficiency genetics physiology von Willebrand Factor / metabolism
来 源:
DOI:10.1161/ATVBAHA.113.301924
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