关键词: Allosteric modulation BRET competition assays BRET kinetics and dose–response assays BRET saturation assays Bioluminescence resonance energy transfer (BRET) G protein-coupled receptors (GPCRs) GPCR–RTK heteroreceptor complexes Heterodimerization Heteroreceptor complexes Homodimerization Receptor tyrosine kinases (RTKs) Receptor–receptor interactions
Mesh : Adenosine / analogs & derivatives chemistry pharmacology Adenosine A2 Receptor Agonists / chemistry pharmacology Binding, Competitive Bioluminescence Resonance Energy Transfer Techniques / methods Dose-Response Relationship, Drug Fibroblast Growth Factor 2 / chemistry metabolism Gene Expression Green Fluorescent Proteins / genetics metabolism HEK293 Cells Humans Kinetics Luciferases, Renilla / genetics metabolism Phenethylamines / chemistry pharmacology Plasmids Protein Binding Protein Multimerization Protein Transport Receptor, Adenosine A2A / chemistry genetics metabolism Receptor, Fibroblast Growth Factor, Type 1 / chemistry genetics metabolism Signal Transduction
来 源: DOI:10.1016/B978-0-12-408143-7.00008-6