肺早衰和细胞衰老在特发性肺纤维化和 COPD / 肺气肿发病机制中的作用.
关键词: AECII COPD CPFE EMT ER FF FIP Hsp27 IPF LAM5γ2 SASP TGF UIP UPR chronic obstructive pulmonary disease combined pulmonary fibrosis and emphysema endoplasmic reticulum epithelial mesenchymal transition familial interstitial pneumonia fibroblast foci heat shock protein 27 idiopathic pulmonary fibrosis laminin-5-γ2 chain senescence-associated secretory phenotype transforming growth factor type-II alveolar epithelial cells unfolded protein response usual interstitial pneumonia
Mesh : Cellular Senescence Emphysema / pathology Humans Idiopathic Pulmonary Fibrosis / pathology Lung / pathology Pulmonary Disease, Chronic Obstructive / pathology Stress, Physiological
来 源:
DOI:10.1016/j.trsl.2013.06.004
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