关键词: Endemic mycosis Micosis endémica Paracoccidioidomicosis Paracoccidioidomycosis Pediatrics Pediatría

Mesh : Amphotericin B / therapeutic use Anemia / etiology Antifungal Agents / therapeutic use Argentina Child Child, Preschool Deoxycholic Acid / therapeutic use Diagnosis, Differential Drug Combinations Endemic Diseases Female Fever / etiology Fungemia / diagnosis Hepatomegaly / etiology Humans Ileus / etiology Itraconazole / therapeutic use Lymphatic Diseases / etiology Lymphoproliferative Disorders / diagnosis Male Neoplasms / diagnosis Osteolysis / etiology Paracoccidioidomycosis / complications diagnosis drug therapy epidemiology Splenomegaly / etiology

来  源:   DOI:10.1016/j.riam.2013.05.013   PDF(Sci-hub)

Abstract:
BACKGROUND: Paracoccidioidomycosis is the most frequent systemic mycosis in Latin America, caused by the dimorphic fungus Paracoccidioides. Paracoccidioidomycosis in children is uncommon. Our aim is to describe clinical features of patients who had a confirmed diagnosis of paracoccidioidomycosis in our hospital in the last 10 years.
METHODS: We describe 4 cases of paracoccidioidomycosis in previously healthy children from the north of our country. Diagnoses were made by biopsy or culture.
CONCLUSIONS: The diagnosis of paracoccidioidomycosis should be considered in a patient coming from regions where Paracoccidioides is endemic, and presenting with a lymphoproliferative syndrome, anemia, eosinophilia and hypergammaglobulinemia.
摘要:
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