PDF(Sci-hub)
Abstract：
OBJECTIVE: To further the understanding of growing pains (GP), in particular, the nature of this pain disorder.
METHODS: This study included 33 children aged 5-12 years who met criteria for GP (cases) and 29 children without GP of similar age and sex (controls). Nineteen controls were siblings of cases. GP was diagnosed by standard consensus questionnaires. A questionnaire addressed characteristics of the pain and family history of GP. Evidence for peripheral neuropathic disorder was tested by somatosensory testing and provocation tests of peripheral nerves. Somatosensory testing by a blinded researcher involved threshold determination and/or response magnitude to nonpainful stimuli including touch, dynamic brush, cold, vibration, and deep pressure applied to limb and abdominal sites.
RESULTS: Distributional, temporal, and quality characteristics of the pain were in accordance with published descriptions. There was no indication of primary musculoskeletal disorder. No evidence was found that GP is a peripheral neuropathic pain syndrome. There were minor but statistically significantly increased responses to cutaneous cold, vibration, and to deep pressure stimuli in cases compared to controls, evident in a wider distribution than the symptomatic lower limbs.
CONCLUSIONS: GP is a regional pain syndrome with evidence in this study of mild widespread disorder of somatosensory processing.
METHODS: This study included 33 children aged 5-12 years who met criteria for GP (cases) and 29 children without GP of similar age and sex (controls). Nineteen controls were siblings of cases. GP was diagnosed by standard consensus questionnaires. A questionnaire addressed characteristics of the pain and family history of GP. Evidence for peripheral neuropathic disorder was tested by somatosensory testing and provocation tests of peripheral nerves. Somatosensory testing by a blinded researcher involved threshold determination and/or response magnitude to nonpainful stimuli including touch, dynamic brush, cold, vibration, and deep pressure applied to limb and abdominal sites.
RESULTS: Distributional, temporal, and quality characteristics of the pain were in accordance with published descriptions. There was no indication of primary musculoskeletal disorder. No evidence was found that GP is a peripheral neuropathic pain syndrome. There were minor but statistically significantly increased responses to cutaneous cold, vibration, and to deep pressure stimuli in cases compared to controls, evident in a wider distribution than the symptomatic lower limbs.
CONCLUSIONS: GP is a regional pain syndrome with evidence in this study of mild widespread disorder of somatosensory processing.
摘要：
目的：为了进一步了解生长痛（GP），特别是,这种疼痛障碍的性质。
方法：这项研究包括33名符合GP标准的5-12岁儿童（病例）和29名年龄和性别相似的无GP儿童（对照）。19个对照是病例的兄弟姐妹。GP是通过标准共识问卷诊断的。问卷涉及GP的疼痛和家族史的特征。通过体感测试和周围神经激发测试来测试周围神经性疾病的证据。由盲人研究人员进行的体感测试涉及阈值确定和/或对包括触摸在内的非疼痛刺激的响应幅度，动态画笔,冷,振动,对肢体和腹部部位施加深层压力。
结果：分布，temporal,疼痛的质量特征与已发表的描述一致。没有原发性肌肉骨骼疾病的迹象。没有证据表明GP是一种外周神经性疼痛综合征。对皮肤冷的反应轻微但有统计学意义的增加，振动,与对照组相比，深度压力刺激，明显的分布比有症状的下肢更广泛。
结论：GP是一种区域性疼痛综合征，在这项研究中有证据表明轻度广泛的体感加工障碍。
方法：这项研究包括33名符合GP标准的5-12岁儿童（病例）和29名年龄和性别相似的无GP儿童（对照）。19个对照是病例的兄弟姐妹。GP是通过标准共识问卷诊断的。问卷涉及GP的疼痛和家族史的特征。通过体感测试和周围神经激发测试来测试周围神经性疾病的证据。由盲人研究人员进行的体感测试涉及阈值确定和/或对包括触摸在内的非疼痛刺激的响应幅度，动态画笔,冷,振动,对肢体和腹部部位施加深层压力。
结果：分布，temporal,疼痛的质量特征与已发表的描述一致。没有原发性肌肉骨骼疾病的迹象。没有证据表明GP是一种外周神经性疼痛综合征。对皮肤冷的反应轻微但有统计学意义的增加，振动,与对照组相比，深度压力刺激，明显的分布比有症状的下肢更广泛。
结论：GP是一种区域性疼痛综合征，在这项研究中有证据表明轻度广泛的体感加工障碍。
