利用位置效应和吉普赛逆转录病毒绝缘体来设计精确表达的转基因。
Mesh : Animals Animals, Genetically Modified Attachment Sites, Microbiological / genetics Chromatin / physiology Cytoskeletal Proteins / genetics metabolism Drosophila Proteins / genetics metabolism Drosophila melanogaster / genetics growth & development metabolism Female Gene Expression Regulation Genome, Insect / genetics HSP70 Heat-Shock Proteins / genetics metabolism Insulator Elements / genetics Larva / metabolism Molecular Sequence Data Myogenic Regulatory Factors / genetics metabolism Phenotype Plasmids Receptors, Notch / genetics metabolism Recombination, Genetic Retroviridae / genetics Saccharomyces cerevisiae Proteins / genetics metabolism Tissue Distribution Transgenes / physiology Wings, Animal / physiology
来 源:
DOI:10.1038/ng.101
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