人乳腺癌中 Notch 信号的研究。
Mesh : Adaptor Proteins, Signal Transducing Amyloid Precursor Protein Secretases / antagonists & inhibitors metabolism Apoptosis / physiology Basic Helix-Loop-Helix Transcription Factors / genetics metabolism Breast / metabolism pathology Breast Neoplasms / genetics metabolism pathology Calcium-Binding Proteins / genetics metabolism Cell Cycle / physiology Cell Line, Tumor Cell Proliferation Homeodomain Proteins / genetics metabolism Humans Intercellular Signaling Peptides and Proteins / genetics metabolism Membrane Proteins / genetics metabolism Protease Inhibitors / pharmacology Proto-Oncogene Proteins / genetics metabolism RNA, Messenger / genetics metabolism RNA, Neoplasm / genetics metabolism Receptor, Notch1 / genetics metabolism Receptor, Notch3 Receptor, Notch4 Receptors, Notch / genetics metabolism Reverse Transcriptase Polymerase Chain Reaction Serrate-Jagged Proteins Signal Transduction Transcription Factor HES-1 Up-Regulation