Mesh : Adjuvants, Immunologic / administration & dosage therapeutic use Administration, Topical Adult Aminoquinolines / administration & dosage therapeutic use Child Combined Modality Therapy Cryotherapy Female Hand Heel Humans Imiquimod Interferon Inducers / administration & dosage therapeutic use Male Salicylic Acid / administration & dosage therapeutic use Toes Warts / drug therapy therapy

来  源:   DOI:10.1067/mjd.2002.126582   PDF(Sci-hub)

Abstract:
Imiquimod is an immunomodulator with indirect antiproliferative and antiviral properties known to be effective against anogenital warts. However, its use for common warts has not been validated in prospective, controlled trials. We present 3 anecdotal case reports illustrating one treatment approach for a spectrum of resistant, common warts with combination therapy consisting of cryosurgery followed by administration of imiquimod and salicylic acid. The efficacy of this combined destructive and immunomodulatory therapy proved to be 50% to 100% effective after 6 to 9 weeks.
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